It’s hard to read This Close to Happy: A Reckoning with Depression and not feel deeply sad for the author, whose euphemistically tagged “treatment-resistant” depression has followed her since childhood, with multiple severe episodes following stressful life events. But she seems to attribute most of her problems to her upbringing, which was clearly cold, even neglectful but not out-of-bounds cruel — just clueless. It made me wonder whether holding on to the notion that she deserved a better childhood may not have made it even more difficult for her to live with her illness. It also made me wonder why she clung to a mother whom she describes as indifferent and callous well into adulthood. Wouldn’t she be better off to put some physical and mental space between her and her mother? In any case, the book is a reminder of the great travails of depression, and the gap still to be bridged by medicine when it comes to treating it.